PhysiologybioRxivPreprint
The Hypothalamic-Pituitary-Adrenal Axis Orchestrates Energy Homeostasis during Cold Exposure
Mireia Llerins Perez, Xinran Gao, Laura Heimerl…·Yongguo Li
This study identifies the dual role of the HPA axis in regulating energy homeostasis during cold exposure through ACTH-mediated thermogenesis and glucocorticoid-driven hyperphagia.
DOI 10.1101/2025.09.18.677113