Fuyi Liao

The paper uses molecular imaging to detect chronic lung allograft dysfunction by targeting the TGF-β-activating integrin αvβ6 in mouse and human lung transplants.

This study identifies a genetic variant linked to impaired complement regulation that worsens chronic lung allograft dysfunction-free survival by promoting B cell activation and donor-specific antibodies.

This study shows that the ATG16L1 genetic variant impairs macrophage metabolism, leading to lung transplant rejection, and suggests targeting glycolysis could prevent chronic lung allograft dysfunction.