Sonia Stefanovic

The paper shows that maternal diabetes and Nkx2-5 haploinsufficiency together cause severe cardiac defects in mice, with single-cell multiomic data revealing transcriptional and chromatin changes.

This study investigates the role of Hoxb1 in regulating cardiac progenitor cell patterning and differentiation, showing its negative regulation of posterior SHF differentiation and its impact on congenital heart defects.

This study shows that ectopic Hoxb1 expression in neural crest cells causes craniofacial and cardiac malformations, highlighting its role in development.