Sudeep Ghimire

This study investigates how nasal microbiota colonization in germ-free pigs affects immune responses and gut-lung axis interactions, showing antibiotic disruption of microbial diversity and immune gene expression.

This study identifies inflammatory gene expression changes in oligodendroglial lineage cells during EAE using RiboTag-based RNA-Seq, revealing their role in neuroinflammation.

The paper shows that indole lactate (ILA), reduced in MS, restores gut microbiome metabolic balance, promoting remyelination and reducing neuroinflammation.

The paper identifies key microbial interactions and metabolic pathways that confer resistance to C. difficile invasion using synthetic and clinical communities.

This study uses C. elegans to screen human gut microbiota for colonization and resistance against C. difficile, finding 46% colonization success and 50% in vivo inhibition of C. difficile.