Author
Karlsruhe Institute of TechnologyORCID 0000-0001-7777-2306Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Tom Seitz, Julian Köngeter, Susanne Klute…·Fabian Zech
The paper identifies Laudanosine as an inhibitor of TPC2-dependent viral entry, effective against Ebola and related viruses without cytotoxicity.
Susanne Klute, Rayhane Nchioua, Arne Cordsmeier…·Konstantin M. J. Sparrer
The paper shows that the T9I mutation in the SARS-CoV-2 E protein confers autophagy resistance in Omicron variants, contributing to their spread.
Fabian Zech, Christoph Jung, Armando Rodríguez…·Frank Kirchhoff
This paper optimizes a HIV-1 entry inhibitor peptide using ReaxFF molecular dynamics simulations, reducing its size while maintaining or improving antiviral activity.
Qingxing Wang, Sabrina Noettger, Qinya Xie…·Frank Kirchhoff
The paper identifies key mutations in SARS-CoV-2 and bat coronaviruses that affect ACE2 receptor usage across different species and shows that vaccinated individuals' sera neutralize bat Sarbecovirus Spike proteins.