Rayhane Nchioua

This study identifies Regnases as antiviral restriction factors in humans, showing they inhibit RNA viruses but not DNA viruses, with varying substrate selectivity among the four Regnases.

This study identifies that HIV-2 evades ZAP restriction through adaptations in the U3 LTR region despite having higher CpG levels compared to HIV-1 and SIVsmm.

The paper shows that the T9I mutation in the SARS-CoV-2 E protein confers autophagy resistance in Omicron variants, contributing to their spread.

This paper identifies Trypstatin, a Kunitz-type protease inhibitor that inhibits TMPRSS2 and related proteases, showing broad-spectrum antiviral activity against SARS-CoV-2, influenza, and other respiratory viruses.

This study compares the effects of SARS-CoV-2 early strains and Omicron variants on intestinal barrier function using a human gut epithelial model, finding Omicron causes less damage.