Cell BiologybioRxivPreprint
Estrogen receptor alpha mediated repression of PRICKLE1 destabilizes REST and promotes uterine fibroid pathogenesis
Michelle M. McWilliams, Faezeh Koohestani, Wendy N. Jefferson…·Vargheese M. Chennathukuzhi
This study identifies a mechanism by which estrogen receptor alpha suppresses PRICKLE1, leading to REST loss and promoting uterine fibroid development.
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