NeurosciencebioRxivPreprint
Intrabody-guided synapse proteomics defines pyramidal neuron input architecture and uncovers early remodeling in a mouse model of Alzheimer's disease
Dan Dascenco, Gabriele Marcassa, Anastasia Mallopoulou…·Joris de Wit
The paper uses an intrabody-guided proximity-labeling strategy to map postsynaptic proteomes in hippocampal CA1 pyramidal neurons and identifies early synaptic remodeling in an Alzheimer's disease mouse model.
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