Lee Ann Garrett‐Sinha

This study shows that aging leads to senescent-like neutrophils in mice, which have reduced antimicrobial function and altered transcriptional responses to Streptococcus pneumoniae.

The paper identifies regulatory elements controlling Ets1 expression in B cells but not T cells, using epigenetic and reporter assays in mice.

The paper shows that narcolepsy with cataplexy is caused by epigenetic silencing of hypocretin neurons, not their destruction, using QRFP as a marker and methylation analysis.