Eiji Hara

This study identifies dysregulation of the p16-CDK6 axis in HPV-unrelated p16-positive oropharyngeal carcinomas, revealing a distinct molecular mechanism and clinical implications.

The paper identifies issues with the p16-3MR mouse model for in vivo bioluminescence imaging, showing that fur shaving is necessary for accurate signal detection and that previous results may be unreliable.

This study identifies p16High immune cells as critical for disease tolerance, showing they enhance survival in various conditions and extend healthspan by maintaining low adenosine levels.