NeuroscienceCell ReportsPeer-reviewed
Ca2+-dependent phosphodiesterase 1 regulates the plasticity of striatal spiny projection neuron glutamatergic synapses
Shenyu Zhai, Shintaro Otsuka, Jian Xu…·Dalton James Surmeier
The paper identifies Ca2+-dependent phosphodiesterase 1 (PDE1) as a regulator of NO-induced long-term depression (NO-LTD) in striatal spiny projection neurons, linking it to synaptic plasticity and Parkinson's disease.
13 citations