Yang Xiao

OmicGlaze provides a spatial multi-omic framework to analyze TBI, identifying gene regulatory networks and region-specific biological changes.

SuperFocus integrates histopathology with single-cell spatial multi-omics data from spot-based measurements, improving accuracy by 28-73% over existing methods.

This study develops nanomaterials that capture cell-free DNA to reduce inflammation in periodontitis and atherosclerosis by modulating macrophage lipid markers.

SPACEc provides a Python workflow for analyzing multiplexed imaging data with interactive tools for image processing, segmentation, and spatial analysis.

This paper introduces Patho-DBiT, a method for spatial transcriptomics in FFPE tissues, enabling RNA biology analysis including splicing, variants, and regulatory networks in clinical samples.

This study examines the effects of chronic and acute fentanyl exposure on midbrain organoids, finding that chronic treatment arrests neuronal development and alters synaptic pathways.

This paper introduces spatial-ATAC-seq, a method for spatially resolved chromatin accessibility profiling at the cellular level, and demonstrates its application in mouse embryos and human tonsil tissue.

The paper identifies Gli1+ stem cells in the enthesis, shows their multipotency and therapeutic potential for tendon regeneration.

DBiT-seq enables high-spatial-resolution multi-omics mapping of mouse embryos by deterministic barcoding, revealing tissue types and fine features like retinal pigmented epithelium and microvasculature.

The paper was withdrawn due to a duplicate posting and directs readers to the current version on bioRxiv.