Molecular BiologyNaturePeer-reviewed
Molecular determinants of β-arrestin coupling to formoterol-bound β1-adrenoceptor
Yang Lee, Tony Warne, Rony Nehmé…·Christopher G. Tate
This paper determines the cryo-EM structure of the β1AR-βarr1 complex bound to formoterol and compares it to the β1AR-Gs complex, revealing structural differences that inform biased agonism.
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