Author
MRC Laboratory of Molecular BiologyORCID 0000-0002-8574-3588Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Qingchao Chen, Anastasiia Gusach, Aurora Diamante…·David Mordechai Favara
The paper determines the cryo-EM structure of ADGRL4 coupled to Gq, showing weak Gq coupling and distinct interactions compared to other GPCRs, supporting its role in cancer.
Anastasiia Gusach, Yang Lee, Armin Nikpour Khoshgrudi…·Christopher G. Tate
The paper determines the cryo-EM structure of mTAAR7f bound to DMCH, revealing its unique binding site and activation mechanism distinct from ORs.
Yang Lee, Tony Warne, Rony Nehmé…·Christopher G. Tate
This paper determines the cryo-EM structure of the β1AR-βarr1 complex bound to formoterol and compares it to the β1AR-Gs complex, revealing structural differences that inform biased agonism.