Peng Huang

This study shows that Pax9 is essential for anterior identity and proper deployment of sclerotome cells in the caudal fin of zebrafish, leading to fusion with the anal fin and altered skeletal development.

This study shows Foxa2 maintains floor plate identity and regulates Sonic hedgehog signaling in zebrafish spinal cord development.

The paper shows that Gli signaling controls lumen retraction in the zebrafish spinal cord, which drives roof plate cell extension during development.

The paper shows brain pericytes come from multiple sources, including fibroblasts, and their numbers adjust with vessel development.

The paper quantifies Shh response dynamics in zebrafish neural progenitors and finds significant heterogeneity between Shh response and fate choice.

This study shows that B cell-induced lymph node stromal remodeling impairs neutrophil response to secondary Staphylococcus aureus infection by disrupting the FRC-conduit network.

The paper shows that Pdgfab/Pdgfra-mediated chemoattraction guides sclerotome-derived fibroblast precursors to specific locations in zebrafish, where they differentiate into distinct subtypes.

The paper shows that some nephrons in zebrafish kidneys originate from somites, challenging the belief that kidneys only come from intermediate mesoderm.

This study shows BMP signaling is necessary and sufficient for sclerotome induction in zebrafish and reveals distinct BMP requirements for lineage diversification.

The paper uses single-cell RNA sequencing to identify fibroblast subtypes in zebrafish and shows that perivascular/interstitial fibroblasts regenerate tenocytes via Hedgehog signaling.

This study identifies nkx3.1-expressing precursors in zebrafish that differentiate into brain pericytes and shows their regulation by cxcl12b-Cxcr4 signaling.

This study identifies the sclerotome as the embryonic source of multiple fibroblast subtypes in zebrafish and shows how local signals drive their diversification.

The paper shows that the duration of Notch signaling, not just its level, determines temporal cell fate in zebrafish spinal cord progenitors.

The paper identifies perivascular fibroblasts in zebrafish as a novel cell type contributing to vascular stabilization through ECM secretion and pericyte progenitor function.

The paper investigates how Notch signalling maintains Hedgehog responsiveness in zebrafish spinal cord development through a Gli-dependent mechanism.

The paper uses live imaging and single cell clonal analysis to study the dynamic behaviors of zebrafish embryonic muscle progenitor cells during quiescence and activation.