Author

Nagarajan Nandagopal

Harvard UniversityORCID 0000-0002-0469-6549Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Galit LahaviD· 2 shared Sean G. MegasoniD· 2 shared Alexsandra Terrio· 1 shared Andrea R. TentneriD· 1 shared Anna Cha· 1 shared Ashwini JambhekariD· 1 shared Bill JiaiD· 1 shared Caroline ComenhoiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Galit LahavORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Heterogeneity of Sonic Hedgehog response dynamics and fate specification in single neural progenitors

Fengzhu Xiong, Andrea R. Tentner, Nagarajan Nandagopal, Tom W. Hiscock, Peng Huang, Sean G. Megason

The paper quantifies Shh response dynamics in zebrafish neural progenitors and finds significant heterogeneity between Shh response and fate choice.

bioRxiv · Mar 7, 2026Developmental Biology

Neural plate morphogenesis and pre-patterning enable specification of intermediate progenitors in the spinal cord

Nagarajan Nandagopal, Anna Cha, Bill Jia, Hongyu Liao, Caroline Comenho, Galit Lahav, Daniel E. Wagner, Tony Yu-Chen Tsai, Sean G. Megason

The paper shows intermediate spinal cord progenitors are specified through neural plate dynamics and signaling, not direct morphogen exposure.

bioRxiv · Jan 9, 2025 · PreprintDevelopmental Biology

Signal integration by a bHLH circuit enables fate choice in neural stem cells

Nagarajan Nandagopal, Alexsandra Terrio, Fernando P. Vicente, Ashwini Jambhekar, Galit Lahav

The paper shows that a bHLH circuit enables neural stem cells to choose astrocytic fate by integrating BMP and LIF signals and suppressing alternative fates.

bioRxiv · Oct 10, 2022 · PreprintSystems Biology

Cis-activation in the Notch signaling pathway

Nagarajan Nandagopal, Leah A. Santat, Michael B. Elowitz

The paper shows cis-ligands can activate Notch receptors, similar to trans-activation, and demonstrates its role in neural stem cell survival and differentiation.

eLife · Jan 10, 2019Peer-reviewedBioinformatics