Author

Alexander Kononov

Cancer Research UKORCID 0000-0001-7971-7095Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Aleksandr IanevskiiD· 1 shared Anil Kumar GiriiD· 1 shared Anu SuomalaineniD· 1 shared Eija JokitaloiD· 1 shared Gulayse Ince-DunniD· 1 shared Helena VihineniD· 1 shared Joni NikkaneniD· 1 shared Olesia IgnatenkoiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Aleksandr IanevskiORCID

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2 papers

Recent·Most cited

NeuroscienceThe Journal of Cell BiologyPeer-reviewedOct 8, 2022

Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes

Olesia Ignatenko, Satu Malinen, Sofiia Rybas…·Anu Suomalainen

This study shows mitochondrial dysfunction in astrocytes disrupts primary ciliary homeostasis, linking mitochondrial stress to ciliary signaling and neurodegenerative disease mechanisms.

63 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedFeb 3, 2020

SynToxProfiler: an approach for top drug combination selection based on integrated profiling of synergy, toxicity and efficacy

Aleksandr Ianevski, Alexander Kononov, Sanna H. Timonen…·Anil Kumar Giri

SynToxProfiler prioritizes drug combinations by integrating synergy, efficacy, and toxicity profiles to improve clinical success likelihood.

69 citationstop 4%

humanexperimental assay

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