Theresa M. Schütze

Species-specific basal fluidization shapes early forebrain development

This study identifies basal fluidization in human neuroepithelia as a tissue-level mechanism driving forebrain expansion, distinct from other great apes and mice.

Human-specific morphoregulatory signatures in basal radial glia characterize neocortex evolution

This study identifies human-specific morphoregulatory signatures in basal radial glia that drive neocortex evolution through comparative chromatin and transcriptional profiling.

Canonical and non-canonical PRC1 differentially contribute to the regulation of neural stem cell fate

The paper compares the roles of canonical and non-canonical PRC1 sub-complexes in neural stem cell regulation during neocortex development, finding canonical PRC1 has a more significant impact.

Epigenome profiling identifies H3K27me3 regulation of extra-cellular matrix composition in human corticogenesis

The paper identifies H3K27me3 regulation of extra-cellular matrix composition in human corticogenesis using Epi-CyTOF and cortical organoids.

Primate-expressed EPIREGULIN promotes basal progenitor proliferation in the developing neocortex

This study shows that primate-specific EPIREGULIN expression enhances basal progenitor proliferation in the developing neocortex, contributing to increased brain size across species.