Shuguang Wang

This paper presents a CRISPR-Cas-based system called VADER for degrading antibiotic resistance genes (ARGs) in environmental biotechnology, achieving 100% ARG elimination in a prototype reactor.

scPrivacy enables privacy-preserving integration of single-cell RNA-seq datasets from multiple institutions for cell type identification.

This paper develops a base-editing tool for Synechococcus elongatus to enable precise genome modifications, enhancing glycogen content through multiplex editing.

The paper compares human and mouse neocortical development using scRNA-seq, finding differences in excitatory neuron trajectories and gene expression but conservation in glial and inhibitory neuron development.