Synthetic BiologyJournal of Biological ChemistryPeer-reviewed
One-for-all gene inactivation via PAM-independent base editing in bacteria
Xin Li, Ying Wei, Shuyan Wang…·Peng‐Fei Xia
This paper introduces XSTART, a PAM-independent base editing system for universal gene inactivation in bacteria, achieving near 100% efficiency but with off-target events.
8 citations