Author

Juliette Steer

Wellcome Sanger InstituteORCID 0000-0001-8086-7955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Andrew Roger BassettiD· 3 shared Florian T. MerkleiD· 2 shared Kaur AlasooiD· 2 shared Natsuhiko KumasakaiD· 2 shared Adib Miraki FeriziD· 1 shared Aleksander M. Gontarczyk· 1 shared Anna S. E. CuomoiD· 1 shared Caia S. DominicusiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersGenomics

Andrew Roger BassettORCID

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4 papers

Recent·Most cited

GenomicsbioRxivPreprintOct 14, 2026

Transcriptomic and phenotypic characterization of Alzheimer's disease risk genes in neurons and astrocytes highlights shared and cell type specific cellular mechanisms

Caia S. Dominicus, Diego Peretti, Geraldine Rodschinka…·Andrew Roger Bassett

The paper uses single-cell transcriptomics and phenotypic analysis of gene knockouts in hiPSC-derived neurons and astrocytes to identify cell-type specific and shared mechanisms of Alzheimer's disease risk genes.

DOI 10.64898/2026.10.13.758778

humanscRNA-seq

𝕏 PostBluesky

NeuroscienceiSciencePeer-reviewedApr 10, 2026

An Alzheimer's disease-associated common regulatory variant in a PTK2B intron alters microglial function

Erica Bello, Kathleen R. Long, Sho Iwama…·Andrew Roger Bassett

The paper validates an Alzheimer's disease-associated SNP in PTK2B that alters microglial function through changes in chromatin accessibility and gene expression.

6 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintAug 18, 2025

Integrated QTL mapping and CRISPR screening in pooled iPSC-derived microglia reveals genetic drivers of neurodegenerative risk

Marta Perez‐Alcantara, Sam J. Washer, Yixi Chen…·Andrew Roger Bassett

The paper integrates QTL mapping and CRISPR screening in iPSC-derived microglia to identify genetic drivers of neurodegenerative risk by linking variants to phenotypes and gene expression.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsNature GeneticsPeer-reviewedMar 1, 2021

Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation

Julie Jerber, Daniel D. Seaton, Anna S. E. Cuomo…·Oliver Stegle

The paper uses single-cell RNA sequencing to study genetic variant effects on dopaminergic neuron differentiation from iPSCs, identifying eQTL and cell fate markers.

303 citationstop 1%

humanscRNA-seq

𝕏 PostBluesky