Author

Patrick Ernst

University of MinnesotaORCID 0000-0001-8103-3602Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Anusua SarkariD· 1 shared Kai CheniD· 1 shared Lufang ZhouiD· 1 shared Margaret LiuiD· 1 shared Matthew David RingeliD· 1 shared Seulhee KimiD· 1 shared Tanvi VaradkariD· 1 shared Yingnan SiiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Anusua SarkarORCID

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1 paper

Recent·Most cited

An Innovative Mitochondrial-targeted Gene Therapy for Cancer Treatment

Kai Chen, Patrick Ernst, Anusua Sarkar, Seulhee Kim, Yingnan Si, Tanvi Varadkar, Matthew David Ringel, Margaret Liu, Lufang Zhou

This paper introduces mLumiOpto, a mitochondrial-targeted gene therapy that disrupts cancer cell mitochondria using light-activated proteins, showing efficacy in reducing tumor burden in mouse models.

Cancer Research · Sep 17, 2024Peer-reviewedCancer Biology