Lufang Zhou

This study identifies Panx2 as a regulator of ER stress-induced Ca2+ dysregulation and inflammatory cardiomyocyte death, showing its role in stabilizing Ca2+ homeostasis and limiting PERK-driven signaling.

This paper introduces mLumiOpto, a mitochondrial-targeted gene therapy that disrupts cancer cell mitochondria using light-activated proteins, showing efficacy in reducing tumor burden in mouse models.