Author

Arkasubhra Ghosh

Narayana NethralayaORCID 0000-0002-6570-5891Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:C. elegans· 1

Frequent Co-Authors

Debasish SinhaiD· 2 shared James T. HandaiD· 2 shared Praveen Machiraju· 2 shared Sayan GhoshiD· 2 shared Stacey Hose· 2 shared Vishnu Suresh BabuiD· 2 shared Abhijit Chowdhury· 1 shared Adam S. ButterworthiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

Debasish SinhaORCID

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Author profile →

4 papers

Recent·Most cited

AKT1-phosphorylated TERT assembles a FOXO3-MYC transcriptional complex that drives ERphagy and proteostasis in post-mitotic RPE

Vishnu Suresh Babu, Sayan Ghosh, Sridhar Bammidi, Ryu Jiwon, Ruchi Sharma, Dominique Meyer, Stacey Hose, Padmanabhan Paranji Pattabiraman, José‐Alain Sahel, Nathan J. Kidley, Natércia F. Braz, Martin J. Slater, Stuart Lang, Arkasubhra Ghosh, James T. Handa, , Debasish Sinha

This paper identifies an AKT1-TERT-FOXO3-MYC transcriptional complex that drives ERphagy and proteostasis in post-mitotic RPE cells under stress.

Autophagy · Oct 26, 2026Peer-reviewedCell Biology

Attenuated adenosine mediated immune-dampening increases natural killer cell activity in early age-related macular degeneration

Archana Padmanabhan Nair, Sayan Ghosh, Vishnu Suresh Babu, Praveen Machiraju, Ying Xin, Ganesh Ram Sahu, Tanuja Arun Vaidya, Jayasree Debnath, Karthik Raja, Santhosh Gopi Krishna Gadde, Thirumalesh MB, Naren Shetty, Aishwarya Saxena, Rohit Shetty, Stacey Hose, , Arkasubhra Ghosh

The paper investigates immune alterations in early AMD, finding elevated NK cell activity and reduced adenosine, suggesting immune imbalance drives disease progression.

bioRxiv · Jan 22, 2025 · PreprintImmunology

Paired transcriptomic analyses of atheromatous and control vessels reveal novel autophagy and immunoregulatory genes in peripheral artery disease

Praveen Machiraju, Rajesh Srinivas, Ramaraj Kannan, Robbie K George, Stephane R B Heymans, Rupak Mukhopadhyay, Arkasubhra Ghosh

The paper identifies novel autophagy and immunoregulatory genes and pathways in PAD plaques through transcriptomic analysis of paired atheromatous and control vessel tissues.

Cells · Jul 28, 2024Peer-reviewedMolecular Biology

South Asian patient population genetics reveal strong founder effects and high rates of homozygosity - new resources for precision medicine

Jeffrey D. Wall, J. Fah Sathirapongsasuti, Ravi Kr Gupta, Anamitra Barik, Rajesh Kumar, Asif Rasheed, Venkatesan Radha, Saurabh Belsare, Ramesh Menon, Sameer Phalke, Anuradha Mittal, John Z. Fang, Deepak Tanneeru, Manjari Deshmukh, Akshi Bassi, , Andrew S. Peterson

The paper characterizes the genetic structure of South Asian populations, identifies founder effects and high homozygosity, and develops a custom SNP array for genetic studies in the region.

bioRxiv · Oct 2, 2020 · PreprintGenomics