Marta Kulis

The paper uses spatial molecular imaging data to map human tonsil architecture and provides an analytical framework for Spatial Immunology.

This paper creates a 3D epigenomic roadmap of human B-cell differentiation, revealing regulatory mechanisms in immunity and cancer.

This study shows KDM6A regulates immune response genes in multiple myeloma by activating NLRC5 and CIITA, and its loss reduces MHC expression, which can be reversed by HDAC3 inhibitors.

This study shows that obesity leads to irreversible mitochondrial dysfunction in visceral adipose tissue, which persists despite lifestyle interventions.

This study examines 3D genome architecture changes during B cell differentiation and in B cell neoplasias using Hi-C and multi-omic data, revealing dynamic compartment shifts and tumor-specific chromatin reorganization.

The paper identifies sampling artifacts in single-cell genomics and proposes solutions to mitigate them in cohort studies.