Author

Dolors Colomer

Hospital Clínic de BarcelonaORCID 0000-0001-7486-8484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Elı́as CampoiD· 2 shared José Ignacio Martín-SuberoiD· 2 shared Marta KulisiD· 2 shared Alba Díaz-Aguilera· 1 shared Alberto Fernández‐MedardeiD· 1 shared Anabel Clemente-Serrano· 1 shared Andrea Olarte-San JuaniD· 1 shared Antonio JuliàiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Elı́as CampoORCID

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3 papers

Recent·Most cited

Targeting SOS1 synergistically enhances efficacy of BCR/ABL tyrosine kinase inhibitors and overcomes resistance in chronic myeloid leukemia

Rósula García‐Navas, Carmela Gómez, Anabel Clemente-Serrano, Belen Zamora-Valdivieso, Sara Pérez-Gutiérrez, Andrea Olarte-San Juan, Alba Díaz-Aguilera, Sonsoles Calvo-Jimenez, Nuria Calzada, Alberto Fernández‐Medarde, Magdalena Sierra, Fermin M. Sanchez-Guijo, Dolors Colomer, Robyn L. Schenk, Marco H. Hofmann, , Eugenio Santos

This study shows that combining SOS1 inhibitor BI-3406 with BCR/ABL TKIs like imatinib improves survival and overcomes resistance in CML models.

Cell Death and Disease · Aug 12, 2026Peer-reviewedCancer Biology

Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

Roser Vilarrasa‐Blasi, Paula Soler-Vila, Núria Verdaguer-Dot, Núria Russiñol, Marco Di Stefano, Vicente Chapaprieta, Guillem Clot, Irene Farabella, Pol Cuscó, Marta Kulis, Xabier Agirre, Felipe Prósper, Renée Beekman, Sı́lvia Beà, Dolors Colomer, , José Ignacio Martín-Subero

This study examines 3D genome architecture changes during B cell differentiation and in B cell neoplasias using Hi-C and multi-omic data, revealing dynamic compartment shifts and tumor-specific chromatin reorganization.

Nature Communications · Jan 28, 2021Peer-reviewedGenomics

Sampling artifacts in single-cell genomics cohort studies

Ramon Massoni-Badosa, Giovanni Lo Iacono, Cátia Moutinho, Marta Kulis, Núria Palau, Doménica Marchese, Javier Rodríguez‐Ubreva, Esteban Ballestar, Gustavo Rodríguez-Esteban, Sara Marsal, Marta Aymerich, Dolors Colomer, Elı́as Campo, Antonio Julià, José Ignacio Martín-Subero, Holger Heyn

The paper identifies sampling artifacts in single-cell genomics and proposes solutions to mitigate them in cohort studies.

bioRxiv · Jan 15, 2020 · PreprintGenomics