Author

Emmanuèle Helfer

Centre National de la Recherche ScientifiqueORCID 0000-0001-8123-0964Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Cécile JebaneiD· 2 shared Anne M. CharrieriD· 1 shared Anotida MadzvamuseiD· 1 shared Ekaterina BoyarchukiD· 1 shared Francesca BallatoreiD· 1 shared Guillaume LamouriD· 1 shared Guillaume VelascoiD· 1 shared Jack LlewellyniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiophysics

Cécile JebaneORCID

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3 papers

Recent·Most cited

BiophysicsPLoS Computational BiologyPeer-reviewedJul 30, 2026

A geometric-surface PDE model for cell-nucleus translocation through confinement

Francesca Ballatore, Anotida Madzvamuse, Cécile Jebane…·Rachèle Allena

This paper introduces a geometric-surface PDE model to simulate cell-nucleus translocation through confined spaces, showing that surface tension and geometry are key factors in translocation efficiency.

2 citations

deep learningstatistical model

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Molecular BiologybioRxivPreprintNov 28, 2025

Epigenetic control of nuclear mechanics and cellular migration via histone H3 lysine 9 methylation at Lamina-Associated Domains

Silvia Comunian, Valentin Petit, Guillaume Velasco…·Slimane Ait‐Si‐Ali

This study shows that SETDB1 regulates LADs and nuclear mechanics by modulating H3K9me3, affecting cancer cell migration without major transcriptional changes.

DOI 10.1101/2025.11.28.690983

humanChIP-seq

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Cell BiologyiSciencePeer-reviewedJul 20, 2024

Substrate Stiffness Reshapes Layer Architecture and Biophysical Features of Human Induced Pluripotent Stem Cells to Modulate their Differentiation Potential

Jack Llewellyn, Anne M. Charrier, Rossana Cuciniello…·Rosanna Dono

This study shows that substrate stiffness affects hiPSC layer structure and biophysical properties, enhancing mesendoderm differentiation on softer substrates.

16 citations

humanbulk RNA-seq

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