Author

Jack Llewellyn

Royal Veterinary CollegeORCID 0000-0002-3056-6262Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna HoyleiD· 1 shared Anne CharrieriD· 1 shared Charlotte E. L. MelloriD· 1 shared Chavaunne T. ThorpeiD· 1 shared Emmanuèle Helfer· 1 shared G. Berridge· 1 shared Hollie Delo· 1 shared Iolanda VendrelliD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCell Biology

Anna HoyleORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 27, 2026

Senescent tenocytes drive an age-associated loss of cell-extracellular matrix homeostasis, which can be partially restored using dihydroresveratrol

Jack Llewellyn, Nodoka Iwasaki, Anna Hoyle…·Chavaunne T. Thorpe

This study shows that senescent tenocytes contribute to age-related tendon degeneration and that dihydroresveratrol can partially restore matrix homeostasis.

DOI 10.64898/2026.07.26.740761

proteomicsmetagenomics

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Cell BiologybioRxivPreprintMay 25, 2026

Quantifying the Environmental Impact of Cell Culture

Isobel Taylor-Hearn, Jack Llewellyn, Charlotte E. L. Mellor, Martin Farley

The paper introduces an open-source calculator to estimate plastic use and CO2 emissions from lab protocols, demonstrating how adjustments can reduce waste without compromising experimental efficiency.

DOI 10.64898/2026.05.21.720586

𝕏 PostBluesky

Cell BiologybioRxivPreprintFeb 1, 2024

Substrate Stiffness Reshapes Layer Architecture and Biophysical Features of Human Induced Pluripotent Stem Cells to Modulate their Differentiation Potential

Jack Llewellyn, Anne Charrier, Emmanuèle Helfer, Rosanna Dono

This study shows that substrate stiffness affects hiPSC layer structure and biophysical properties, enhancing mesendoderm differentiation on softer substrates.

DOI 10.1101/2024.02.01.578393

humanbulk RNA-seq

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