Author

Benjamin R. Schrank

Massachusetts General HospitalORCID 0000-0001-8138-4250Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Alefiya Dhilla AlbersiD· 1 shared Alexis C. GomeziD· 1 shared Allana Schooley· 1 shared André NussenzweigiD· 1 shared Aslı ŞahiniD· 1 shared Bradley T. HymaniD· 1 shared Darian FardiD· 1 shared Elena RattiiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alefiya Dhilla AlbersORCID

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2 papers

Recent·Most cited

Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedDec 23, 2022

ARP2/3- and resection-coupled genome reorganization facilitates translocations

Jennifer Zagelbaum, Allana Schooley, Junfei Zhao…·Jean Gautier

The paper shows that ARP2/3-dependent nuclear actin polymerization and DNA end-resection coordinate genome reorganization to facilitate homology-directed repair and prevent translocations.

68 citationstop 3%

humanDNA methylation

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NeurosciencebioRxivPreprintJan 19, 2018

Genome-encoded Cytoplasmic Double-Stranded RNAs, Found in C9ORF72 ALS-FTD Brain, Provoke Propagated Neuronal Death

Steven Rodriguez, Benjamin R. Schrank, Aslı Şahin…·Mark W. Albers

The paper shows that cytoplasmic double-stranded RNA (cdsRNA) from C9ORF72 expansions in ALS-FTD brains triggers IFN-I signaling and neuronal death through a viral-mimetic mechanism.

5 citations

humanDNA methylation

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