Author

Allana Schooley

University of Massachusetts Chan Medical School

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Job DekkeriD· 4 shared Jean GautieriD· 2 shared Jennifer Zagelbaum· 2 shared Junfei ZhaoiD· 2 shared Max E. GottesmaniD· 2 shared Raúl RabadániD· 2 shared André NussenzweigiD· 1 shared Benjamin R. SchrankiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersMolecular Biology

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4 papers

Recent·Most cited

Dynamic changes in chromosome and nuclear architecture during maturation of normal and ALS C9orf72 motor neurons

Özgün Uyan, Snehal Sambare, Marlies E. Oomen, Nicholas Wightman, Allana Schooley, Joseph R. Klim, Houda Belaghzal, Özkan Aydemir, Betül Akgöl Oksuz, Zeynep Sena AGIM USLU, Kevin C. Eggan, Robert H. Brown, Job Dekker

The paper examines changes in chromosome conformation, nuclear organization, and transcription during motor neuron maturation in control and ALS C9orf72 mutant cells, finding delayed maturation in disease models.

bioRxiv · Sep 22, 2025 · PreprintNeuroscience

Interphase chromosome conformation is specified by distinct folding programs inherited via mitotic chromosomes or through the cytoplasm

Allana Schooley, Sergey V. Venev, Vasilisa Aksenova, Emily Navarrete, Mary Dasso, Job Dekker

The paper investigates how interphase chromosome conformation is re-established after mitosis by distinguishing between chromosome-intrinsic and cytoplasmic inheritance mechanisms.

bioRxiv · Sep 16, 2024 · PreprintGenomics

Mechanisms of insertions at a DNA double-strand break

Jaewon Min, Junfei Zhao, Jennifer Zagelbaum, Jina Lee, Sho Takahashi, Portia Cummings, Allana Schooley, Job Dekker, Max E. Gottesman, Raúl Rabadán, Jean Gautier

The paper develops Indel-Seq to study insertion mechanisms at DNA double-strand breaks, finding insertions arise from transcription and require DNA-PK and ssDNA overhangs.

Molecular Cell · Jul 1, 2023Peer-reviewedMolecular Biology

ARP2/3- and resection-coupled genome reorganization facilitates translocations

Jennifer Zagelbaum, Allana Schooley, Junfei Zhao, Benjamin R. Schrank, Elsa Callén, Shan Zha, Max E. Gottesman, André Nussenzweig, Raúl Rabadán, Job Dekker, Jean Gautier

The paper shows that ARP2/3-dependent nuclear actin polymerization and DNA end-resection coordinate genome reorganization to facilitate homology-directed repair and prevent translocations.

Nature Structural & Molecular Biology · Dec 23, 2022Peer-reviewedMolecular Biology