NeurosciencebioRxivPreprint
Both the low-density lipoprotein receptor and apolipoprotein E define blood-borne high-density lipoprotein entry into the brain.
Sofia Kakava, Mary Gonzalez Melo, Wai Hang Cheng…·Jérôme Robert
The paper investigates how high-density lipoproteins (HDL) cross the blood-brain barrier, showing that LDLR and apoE composition determine HDL entry and brain localization.
DOI 10.1101/2025.05.23.655828