Author

Mary Gonzalez Melo

University of ZurichORCID 0000-0001-5261-0116Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Arnold von EckardsteiniD· 2 shared Alaa OthmaniD· 1 shared Andreas J. HülsmeieriD· 1 shared Anna KovilakathiD· 1 shared Antonis KatsoulasiD· 1 shared Belle Vivica van RosmaleniD· 1 shared Benjamin GilletiD· 1 shared Bin YaniD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

Arnold von EckardsteinORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 25, 2025

Dyslipidemic SPTLC3 Integrates Bile Acid-FXR Signaling with Sphingolipid Remodeling in MASLD

Michele Visentin, Zhibo Gai, Anna Kovilakath…·Museer A. Lone

This study identifies SPTLC3's role in integrating bile acid-FXR signaling with sphingolipid remodeling in MASLD, showing its dysregulation in human liver and association with disease.

DOI 10.1101/2025.08.25.672208

humanmouse

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NeurosciencebioRxivPreprintMay 23, 2025

Both the low-density lipoprotein receptor and apolipoprotein E define blood-borne high-density lipoprotein entry into the brain.

Sofia Kakava, Mary Gonzalez Melo, Wai Hang Cheng…·Jérôme Robert

The paper investigates how high-density lipoproteins (HDL) cross the blood-brain barrier, showing that LDLR and apoE composition determine HDL entry and brain localization.

DOI 10.1101/2025.05.23.655828

mouseexperimental assay

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Developmental BiologybioRxivPreprintMay 18, 2023

Dual-topology of collagen XV and tenascin C acts in concert to guide and shape developing motor axons

Laurie Nemoz-Billet, Martial Balland, Laurent Gilquin…·Sandrine Bretaud

The paper identifies Collagen XV-B and Tenascin C as ECM components guiding motor axon growth through their dual topology and stiffness in zebrafish.

DOI 10.1101/2023.05.18.541309

zebrafishscRNA-seq

𝕏 PostBluesky