Wei-Hsiang Lin

The paper develops a time-resolved single-cell pipeline to analyze antimicrobial peptides in E. coli, revealing two classes with opposing functional trade-offs in their mechanisms and efficacy against biofilms.

The paper shows genome concentration limits transcription and affects proteome composition in E. coli, with effects detectable in nutrient-rich conditions.

The paper shows that polysome dynamics in E. coli help segregate chromosomes during cell division, linking this process to cell growth.

This study shows that Caulobacter crescentus daughter cells have different growth rates due to a G1 phase slowdown, mediated by (p)ppGpp, linking growth modulation to asymmetric division and cell cycle regulation.

The paper develops a theoretical framework to explain exponential growth in nonlinear reaction networks, showing how scalability of flux functions and ergodicity of rescaled systems lead to various growth modalities.