Jian‐Young Wu

This paper introduces a low-cost method using pinhole illumination to improve calcium transient detection in densely labeled neuronal tissue, enabling the identification of over 300 neurons in ex vivo brain slices.

This study investigates whether KCNQ-channel openers can restore hippocampal sharp-wave ripples disrupted by glutamate transporter dysfunction in mouse models.

This study shows that sharp wave ripple events occur in zebrafish hippocampal homologue and basolateral amygdala, and are modulated by cholinergic cells.

The paper studies how inhibition controls the speed and stability of traveling waves in cortical networks using computational models and simulations.

This study shows that parvalbumin basket cells are less active during SWRs in a mouse AD model, contributing to memory impairment.

This study evaluates GCaMP-6f's ability to detect subthreshold and fast population neuronal activity, finding it sensitive for low-amplitude events and fast enough for theta oscillations.

This study shows that disrupting perineuronal nets increases sharp wave ripple frequency in the hippocampus of mice.