Panu E. Kovanen

The paper identifies microtubule inhibitors as inducers of immunogenic cell death in MYChigh TNBC, linking MYC-dependent DAMP release to immune activation and tumor protection.

This study identifies enhanced mitochondrial respiration and glutamine-dependent TCA cycle as vulnerabilities in MYChigh breast cancer cells, showing synthetic lethality with complex I inhibitors.

The paper evaluates immunomodulatory drug responses in patient-derived tumor explant models of breast and renal cancer, finding reproducible gene expression and cytokine changes across models.

This study uses deep learning to analyze bone marrow histopathology in MDS patients, linking morphological features to genetic and clinical outcomes.