Cancer BiologyCell ReportsPeer-reviewed
APC coordinates GSK3 phosphorylation of SETD8 to suppress colorectal cancer
Zvi Cramer, Keara Monaghan, Ricardo Petroni…·Christopher J. Lengner
This study identifies SETD8 as a target of APC-coordinated GSK3 phosphorylation in colorectal cancer, showing that phosphorylation suppresses SETD8's oncogenic activity.
DOI 10.1016/j.celrep.2026.117045