Jiong Hu

This study identifies mitochondrial metabolic inflexibility and S-nitrosylation remodeling in a murine HFpEF model and shows ketone supplementation partially rescues metabolic and functional defects.

This study shows that pericyte contact promotes endothelial cell metabolism by transferring lactate via SLC16A3, altering acetylome and lactylome, and enhancing EndMT-like processes.

This study shows that soluble epoxide hydrolase in astrocytes contributes to vascular instability in Alzheimer's disease, and its deletion reduces vascular amyloid burden and preserves vascular structure.

This study identifies ferroptosis as a regulator of lymphatic vessel growth and regression, showing its role in development and injury response through metabolic and lipid pathway mechanisms.