Colin G. McNamara

This study shows that disrupting the gut microbiota increases reward-seeking behavior in male mice and alters brain gene pathways and inflammation.

This study uses closed-loop optogenetic stimulation to modulate theta and gamma oscillations in the motor cortex of mice, showing phase-dependent effects based on neuron type and stimulation protocol.

The paper validates a mathematical model's predictions about neuronal population responses to phase-locked stimulation using ECoG data from Parkinsonian rats.

The paper investigates how reward, effort, and choice are encoded hierarchically across the cortex and basal ganglia during cost-benefit decisions in rats.

This study develops a closed-loop brain stimulation algorithm in parkinsonian rats that modulates beta oscillations by synchronizing stimulation with cortical activity cycles, leading to sustained changes in oscillation amplitude and locomotion.

The paper investigates how Parkinson’s disease affects the sensitivity of subthalamic nucleus neurons to beta-frequency cortical input, showing increased phase-locking in PD patients and frequency-specific responses in rats.

This study demonstrates a system for phase-dependent closed-loop modulation of neural oscillations in Parkinson's disease, showing that stimulation at specific phases can suppress or amplify beta-band oscillations.

This study shows that phase-dependent electrical stimulation can suppress beta oscillations in Parkinson's patients, offering a potential therapeutic strategy.