Haocheng Yu

The paper identifies atypical B cells (ABCs) as mediators of poor response to BCG immunotherapy in high-risk NMIBC patients, linking their expansion and FCRL5 expression to early recurrence.

This study uses deep learning and reference atlases to analyze tumor cell populations in mouse bladder cancer, identifying lineage-specific subpopulations and their therapeutic vulnerabilities.

This study identifies the HLA-E/NKG2A axis as a therapeutic target in BCG-unresponsive bladder cancer by showing its role in immune evasion and impaired effector cell function.

This study identifies C1QA as a consistent biomarker for tissue macrophages and explores its role in anti-microbial pathways.