Author

A. Rangel

Tisch Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Assay:electrophysiology· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. Aboelela· 1 shared A. Demetriou· 1 shared A. Li· 1 shared A. Narasimhan· 1 shared A. Tocheva· 1 shared A.M. FarkasiD· 1 shared Alan SotoiD· 1 shared Amir HorowitziD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Aboelela

Author profile →

3 papers

Recent·Most cited

The HLA-E/NKG2A axis identifies a therapeutic vulnerability in BCG-unresponsive bladder cancer

Bérengère Salomé, Haocheng Yu, Daniel L Ranti, Ying‐Chih Wang, C. Bieber, Pierre‐Etienne Gabriel, Igor Duquesne, Trine Strandgaard, B. Hug, Sean Houghton, Hiranmayi Ravichandran, Elliot Merritt, S. Bang, A. Demetriou, Z. Li, , Amir Horowitz

This study identifies the HLA-E/NKG2A axis as a therapeutic target in BCG-unresponsive bladder cancer by showing its role in immune evasion and impaired effector cell function.

bioRxiv · Sep 2, 2024 · PreprintCancer Biology

Automated patch clamp screening of amiloride and 5-N,N-hexamethyleneamiloride (HMA) analogs identifies 6-iodoamiloride as a potent acid-sensing ion channel inhibitor.

R. K. Finol-Urdaneta, J. R. McArthur, A. Aboelela, R. S. Bujaroski, H. H. Majed, A. Rangel, D. J. Adams, M. Ranson, M. J. Kelso, B. J. Buckley

The paper screens amiloride analogs using automated patch-clamp to identify 6-iodoamiloride as a more potent ASIC1 inhibitor than amiloride.

bioRxiv · Mar 12, 2022Pharmacology & Toxicology

Flow-cell based technology for massively parallelcharacterization of base-modified DNA aptamers

D. Wu, T. Feagin, P. Mage, A. Rangel, L. Wan, D. Kong, A. Li, J. Coller, M. Eisenstein, H. T. Soh

This paper introduces a flow-cell based system for high-throughput characterization of base-modified DNA aptamers using a modified Illumina MiSeq instrument.

bioRxiv · Apr 25, 2020Bioengineering