Chemical Synthesis of Thrombostasin: An Anticoagulant Protein Produced by the Horn Fly Haematobia irritans
Sameer S. Kulkarni, Daniel Ford, Lucas Kambanis…·Richard J. Payne
This study reports the chemical synthesis of thrombostasin and a hepta-glutamate analogue, along with evaluation of their thrombin inhibitory and anticoagulant activity.