Paula A. Klavina

This study shows that metabolic reprogramming of human macrophages using DASA-58 generates hybrid M1/M2 extracellular vesicles with pro-regenerative properties that enhance angiogenesis and osteogenesis.

This study identifies enhanced myeloid cell prothrombotic activity as a novel consequence of trained immunity, mediated by epigenetic changes and acid sphingomyelinase.

This study identifies TF-mediated thrombogenicity in colitogenic CD4+ T cells and shows APC signalling reduces their procoagulant activity in IBD.

The paper uses single-cell transcriptomics and in-situ imaging to study lung mesenchymal cell diversity during development and hyperoxia, finding delayed diversity and emergence of Acta1+ cells under hyperoxic conditions.