Author

Anna Dominik

Trinity College Dublin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Patrick T. WalshiD· 2 shared Shrikanth Chomanahalli BasavarajappaiD· 2 shared Aisling M. RehilliD· 1 shared Conor M. FinlayiD· 1 shared Darren RuaneiD· 1 shared Gemma LeoniD· 1 shared Heather Loughnane· 1 shared James S. O’DonnelliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Patrick T. WalshORCID

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2 papers

Recent·Most cited

Targeting redox imbalance through Nrf2 activation in the inflamed coeliac duodenum.

Heather Loughnane, Shrikanth Chomanahalli Basavarajappa, Anna Dominik, Conor M. Finlay, Séamus Hussey, Darren Ruane, Patrick T. Walsh

This study uses single-cell transcriptomics to show redox imbalance in coeliac duodenum, with decreased Nrf2 activation in key cell types, and demonstrates that Nrf2 activation reduces inflammation.

Clinical & Experimental Immunology · Jan 1, 2026Peer-reviewedImmunology

Tissue factor-dependent colitogenic CD4+ T cell thrombogenicity is regulated by activated protein C signalling.

Gemma Leon, Paula A. Klavina, Aisling M. Rehill, Sarah E. J. Cooper, Anna Dominik, Shrikanth Chomanahalli Basavarajappa, James S. O’Donnell, Seamus Hussey, Patrick T. Walsh, Roger J. S. Preston

This study identifies TF-mediated thrombogenicity in colitogenic CD4+ T cells and shows APC signalling reduces their procoagulant activity in IBD.

bioRxiv · Apr 16, 2024Immunology