David A. Hoey

This study shows that metabolic reprogramming of human macrophages using DASA-58 generates hybrid M1/M2 extracellular vesicles with pro-regenerative properties that enhance angiogenesis and osteogenesis.

This study identifies mechanically-activated osteocyte-derived extracellular vesicles and miR-150-5p as key regulators of osteoclastogenesis and potential therapeutic targets for skeletal diseases.

This study shows that mechanically activated osteocyte-derived extracellular vesicles enhance angiogenesis in a pre-clinical model, suggesting their potential as a pro-angiogenic nanotherapeutic for bone repair.

This study investigates the role of TRPV4 in mechanically regulated prenatal skeletal development, showing its importance in joint cartilage growth and shape through mechanotransduction.