James R. Tribble

This study shows that pantothenate supplementation improves stress resistance and extends lifespan in C. elegans by enhancing coenzyme A metabolism through DAF-16 and pnk-1 pathways.

The paper identifies metabolites from aged muscle that extend lifespan and improve health in C. elegans models of neurodegenerative diseases.

This study shows nicotinamide protects retinal ganglion cells from glaucoma-related damage by improving mitochondrial function and metabolism.

The paper shows that microglia activation occurs in the contralateral eye of unilateral glaucoma models, suggesting the contralateral eye may not be a valid control.

This study identifies early metabolic and inflammatory changes in microglia from a glaucoma mouse model and shows radiation therapy reverses these changes.

This study shows that Protrudin, when overexpressed, supports axon regeneration in the adult central nervous system by acting as a scaffold to organize endoplasmic reticulum, integrins, and Rab11 endosomes in the distal axon.