Author

Akihiro Nakaya

The University of OsakaORCID 0000-0001-8308-6177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Akinori MiyashitaiD· 3 shared Masataka KikuchiiD· 3 shared Norikazu HaraiD· 3 shared Ryozo KuwanoiD· 3 shared Takeshi IkeuchiiD· 3 shared Adam FleisheriD· 1 shared Akiyoshi KakitaiD· 1 shared Angela OliveriD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Akinori MiyashitaORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicineAlzheimer s Research & TherapyPeer-reviewedFeb 27, 2024

Polygenic effects on the risk of Alzheimer's disease in the Japanese population

Masataka Kikuchi, Akinori Miyashita, Norikazu Hara…·Gary R. Conrad

This paper evaluates the polygenic risk score for Alzheimer's disease in Japanese individuals, showing its utility despite genetic differences from European populations.

19 citationstop 4%

humanGWAS summary statistics

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GenomicsHuman Molecular GeneticsPeer-reviewedJan 11, 2020

Disruption of a RAC1-centred protein interaction network is associated with Alzheimer’s disease pathology and causes age-dependent neurodegeneration

Masataka Kikuchi, Michiko Sekiya, Norikazu Hara…·Akihiro Nakaya

The paper identifies RAC1 as a key gene in Alzheimer's disease progression through a protein domain network analysis and validates its role using Drosophila models and miRNA regulation.

43 citations

humanDrosophila

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GenomicsBMC Medical GenomicsPeer-reviewedSep 9, 2019

Enhancer variants associated with Alzheimer’s disease affect gene expression via chromatin looping

Masataka Kikuchi, Norikazu Hara, Mai Hasegawa…·Akihiro Nakaya

The paper identifies enhancer variants linked to Alzheimer's disease that influence gene expression through chromatin looping mechanisms.

74 citationstop 2%

humanwhole-genome sequencing

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