Author

Mai Hasegawa

Brain Research Institute, Niigata University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Akinori MiyashitaiD· 3 shared Masataka KikuchiiD· 3 shared Norikazu HaraiD· 3 shared Takeshi IkeuchiiD· 3 shared Maho MorishimaiD· 2 shared Ryozo KuwanoiD· 2 shared Shigeo MurayamaiD· 2 shared Ai ObinataiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersNeuroscience

Akinori MiyashitaORCID

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Author profile →

3 papers

Recent·Most cited

Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils

Hayato Etani, Sho Takatori, Wenbo Wang, Jumpei Omi, Yusuke Amiya, Aika Akahori, Hirotaka Watanabe, Iki Sonn, Hideyuki Okano, Norikazu Hara, Mai Hasegawa, Akinori Miyashita, Masataka Kikuchi, Takeshi Ikeuchi, Maho Morishima, , Taisuke Tomita

This study identifies GPR34 as a regulator of microglial amyloid β fibril uptake, showing that its agonist enhances fibril clearance and that its expression declines with age and AD progression.

Alzheimer s Research & Therapy · Nov 20, 2025Peer-reviewedNeuroscience

Association of rare APOE missense variants with Alzheimer's disease in the Japanese population

Akinori Miyashita, Ai Obinata, Norikazu Hara, Risa Mitsumori, Daita Kaneda, Yoshio Hashizume, Terunori Sano, Masaki Takao, Ramil Gabdulkhaev, Mari Tada, Akiyoshi Kakita, Akira Arakawa, Maho Morishima, Shigeo Murayama, Yuko Saito, , Takeshi Ikeuchi

The paper identifies APOE rare missense variants in the Japanese population and finds two variants associated with protective effects against Alzheimer's disease.

medRxiv · Nov 5, 2024 · PreprintGenetic & Genomic Medicine

Enhancer variants associated with Alzheimer’s disease affect gene expression via chromatin looping

Masataka Kikuchi, Norikazu Hara, Mai Hasegawa, Akinori Miyashita, Ryozo Kuwano, Takeshi Ikeuchi, Akihiro Nakaya

The paper identifies enhancer variants linked to Alzheimer's disease that influence gene expression through chromatin looping mechanisms.

BMC Medical Genomics · Sep 9, 2019Peer-reviewedGenomics