Author

Melissa D. Mattocks

University of North Carolina at Chapel HillORCID 0000-0001-8317-5284Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adian S. ValdeziD· 1 shared Alexa B. R. McIntyreiD· 1 shared Alexandra C. WallsiD· 1 shared Alexandra SchäferiD· 1 shared Bali PulendraniD· 1 shared Cara W. ChaoiD· 1 shared Catherine TreicheliD· 1 shared Christine MeniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Adian S. ValdezORCID

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2 papers

Recent·Most cited

Computationally designed mRNA-launched protein nanoparticle vaccines

Grace G. Hendricks, Lilit Grigoryan, Mary Jane Navarro, Nicholas Catanzaro, Miranda L. Hubbard, John M. Powers, Melissa D. Mattocks, Catherine Treichel, Alexandra C. Walls, Jimin Lee, Daniel Ellis, Jing Yang Wang, Suna Cheng, Marcos C. Miranda, Adian S. Valdez, , Neil P. King

This paper develops an mRNA-launched nanoparticle vaccine that combines protein nanoparticle and mRNA vaccine advantages, showing enhanced antibody and T cell responses in mice.

Science Translational Medicine · Oct 15, 2025Peer-reviewedImmunology

Altered m6A modification of specific cellular transcripts affects Flaviviridae infection

Nandan S. Gokhale, Alexa B. R. McIntyre, Melissa D. Mattocks, Christopher L. Holley, Helen M. Lazear, Christopher E. Mason, Stacy M. Horner

This study shows that Flaviviridae viruses alter m6A modification of specific host transcripts, affecting viral infection through changes in translation and splicing.

Molecular Cell · Dec 3, 2019Peer-reviewedMolecular Biology