Author

Mariana Beltrán

University of EdinburghORCID 0000-0001-8321-2479Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Neil Cowan HendersoniD· 2 shared Zrinko KozićiD· 2 shared Alexandra LesayováiD· 1 shared Danilo NegroiD· 1 shared David Jonathan PriceiD· 1 shared Grace Wilson· 1 shared Helen Marshall· 1 shared John O. MasoniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersDevelopmental Biology

Neil Cowan HendersonORCID

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2 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedOct 26, 2026

Loss of PAX6 alters the excitatory/inhibitory neuronal ratio in human cerebral organoids

Wai Kit Chan, Shibla Abdulla, Lusi Zhao…·John O. Mason

This study shows that PAX6 deficiency in human cerebral organoids leads to an increased inhibitory neuron population and altered excitatory/inhibitory ratio due to dysregulated PTN-PTPRZ1 signaling.

2 citations

humanexperimental assay

𝕏 PostBluesky

Developmental BiologyMolecular PsychiatryPeer-reviewedMay 4, 2026

ASD mutations in the ciliary gene CEP41 impact development of projection neurons and interneurons in a human cortical organoid model

Kerstin Hasenpusch‐Theil, Alexandra Lesayová, Zrinko Kozić…·Thomas Theil

The paper investigates how ASD mutations in CEP41 affect cortical neuron development in human organoids, finding altered cilia stability and changes in interneuron and projection neuron differentiation.

DOI 10.1038/s41380-026-03615-2

humanscRNA-seq

𝕏 PostBluesky