Cancer BiologybioRxivPreprint
Increased activity of PRMT5-MEP50 complex improves survival of chromosomally unstable cancer cells by increasing tolerance to protein aggregation and proteotoxicity
Maria F. Suárez Peredo Rodríguez, Laura J. Jilderda, Catalina Gaviria Agudelo…·Floris Foijer
The paper shows that increased PRMT5-MEP50 complex activity helps aneuploid cancer cells survive by reducing protein aggregation and proteotoxicity.
DOI 10.1101/2025.09.12.675799